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NDT Advance Access published online on August 1, 2008
Nephrology Dialysis Transplantation, doi:10.1093/ndt/gfn427
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© The Author [2008]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org


Collapsing glomerulopathy and haemophagocytic syndrome related to malaria: a case report

Abdou Niang1, Samira Elfajri Niang2, El Hadji Fary Ka1, Mamadou M. Ka2 and Boucar Diouf1

1 Department of Nephrology, University Hospital Le Dantec 2 Department of Internal Medicine, Pikiné Hospital, Dakar, Sénégal

Correspondence and offprint requests to: Abdou Niang, Department of Nephrology, University Hospital Le Dantec, Dakar, Sénégal. Tel: +221 33 8893870; Fax: +221 33 8216442; E-mail: niangabdou{at}yahoo.com



  Abstract

Authors report a 37-year-old Senegalese woman with no known history of nephropathy who was admitted for fever related to malaria, severe acute renal failure requiring dialysis with nephrotic syndrome. Biological examinations and bone marrow aspiration showed hemophagocytic syndrome. A kidney biopsy found a ‘collapsing glomerulopathy’ (CG). A protracted course of steroids yielded a complete, unexpected remission of the nephrotic syndrome and renal function was normal at 18 months.

Keywords: collapsing glomerulopathy; haemophagocytic syndrome; nephrotic syndrome

Received for publication: 29. 3.08
Accepted in revised form: 4. 7.08


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