NDT Advance Access published online on October 31, 2007
Nephrology Dialysis Transplantation, doi:10.1093/ndt/gfm695
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© The Author [2007]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org
A Rare Case of Acute Renal Failure Due to Massive Renal Allograft Infiltration with Candida Glabrata*
1 Division of Nephrology, Saint Louis University School of Medicine, Saint Louis, MO, USA 2 Department of Internal Medicine, Saint Luke's Hospital, Saint Louis, MO, USA 3 Department of Pathology, Saint Louis University School of Medicine, Saint Louis, MO, USA 4 Division of Abdominal Transplant, Saint Louis University School of Medicine, Saint Louis, MO, USA
Correspondence and offprint requests to: Correspondence and offprint requests to: Bahar Bastani, Division of Nephrology, Department of Internal Medicine, St Louis University School of Medicine, 3635 Vista Avenue, FDT 9, St Louis, 63110 MO, USA. Tel: +1-314-577-8765; Fax: +1-314-771-0784; E-mail: bastanib@slu.edu
Keywords: acute renal failure; alemtuzumab; candida glabrata; renal transplantation; urinary tract infection
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| Introduction |
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Renal transplant patients remain at risk of graft loss due to acute rejection, calcineurin inhibitor toxicity and chronic allograft nephropathy. Less frequent causes include opportunistic infections related to immunosuppressive therapy. However, infections are a major clinical issue in the field of renal transplantation, impacting on graft and patient survival. Fungal infections account for about 5% of infections in renal transplant recipients [1]. Candida species are the most common fungal pathogen, and the most common forms of infection are oral and esophageal candidiases, vascular access device-related and urinary tract infections [2]. The incidence of candidiasis of the renal allograft is rare and not very well documented.
| Case report |
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A 50-year-old white female with a prior medical history of hypertension,
| Renal biopsy findings |
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| Hospital course |
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| Conclusion |
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