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NDT Advance Access published online on October 2, 2007
Nephrology Dialysis Transplantation, doi:10.1093/ndt/gfm676
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© The Author [2007]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Proximal Calciphylaxis Treated With Calcimimetic ‘Cinacalcet’

Ismail A. Mohammed1, Vashisht Sekar2, Abdullah J. Bubtana1, Sandip Mitra1 and Alastair J. Hutchison1

1 Department of Renal Medicine, Manchester Royal Infirmary, Manchester, UK 2 Academic Surgery Unit, University of Manchester, Manchester, UK

Correspondence and offprint requests to: Correspondence and offprint requests to: Ismail A. Mohammed, Registrar in Renal Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK. Tel: +0161-291-6359; E-mail: i.mohammed{at}doctors.net.uk



  Abstract

Calciphylaxis is a rare condition affecting patients suffering from end-stage renal failure, characterised by cutaneous ischaemia and necrosis. The management of calciphylaxis is challenging owing to the lack of optimal medical therapy, although parathyroidectomy has shown some benefit. We present a case of severe proximal calciphylaxis treated with a small dose of the calcimimetic ‘Cinacalcet’.

Keywords: calciphylaxis; cinacalcet; end stage renal failure; haemodialysis; hyperparathyroidism; metastatic calcification

Received for publication: 31. 5.07
Accepted in revised form: 4. 9.07


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