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NDT Advance Access published online on September 22, 2007
Nephrology Dialysis Transplantation, doi:10.1093/ndt/gfm173
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© The Author [2007]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Randomized controlled trials in PD

Peter G. Blake

Division of Nephrology, University of Western Ontario and London Health Sciences Center, London, Canada

Correspondence and offprint requests to: Dr Peter G. Blake, Chair, Division of Nephrology, London Health Sciences Centre, Victoria Hospital, 800 Commissioners Road, East London, Ontario N6A 4G5, UK. Email: peter.blake@lhsc.on.ca

Keywords: peritoneal dialysis; randomized controlled trials; Automated peritoneal dialysis; peritoneal dialysis solutions

The first 150 words of the full text of this article appear below.

The publication of a systematic review comparing continuous ambulatory peritoneal dialysis (CAPD) and automated peritoneal dialysis (APD) in this issue of NDT is very timely [1]. The growth in APD relative to CAPD has been striking over the past decade. Lifestyle factors, in particular, have resulted in more than half of new PD patients in North America using a cycler [2]. Similar trends have been seen in Europe and Japan. This move to APD was initially accompanied by the notion that the therapy was probably superior in terms of its ability to provide higher doses of dialysis and more effective fluid removal [3]. There was also the suggestion, from a randomized trial, that peritonitis might be decreased with APD [4]. Thus medical and lifestyle factors combined to drive the trend.

Recently however, the efficacy of APD has been questioned. In particular, a . . . [Full Text of this Article]


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