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NDT Advance Access published online on September 12, 2006
Nephrology Dialysis Transplantation, doi:10.1093/ndt/gfl544
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© The Author [2006]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Received June 19, 2006
Accepted August 14, 2006

Translational Nephrology

Mast cells and the power of local RAS activation

Harm Peters 1 * and Thomas Unger 2

1 Center for Cardiovascular Research, Charité Universitätsmedizin Berlin, Charité Campus Mitte, Humboldt University, Berlin, Germany; Department of Nephrology, Charité Universitätsmedizin Berlin, Charité Campus Mitte, Humboldt University, Berlin, Germany
2 Center for Cardiovascular Research, Charité Universitätsmedizin Berlin, Charité Campus Mitte, Humboldt University, Berlin, Germany; Institute for Pharmacology and Toxicology, Charité Universitätsmedizin Berlin, Charité Campus Mitte, Humboldt University, Berlin, Germany

* To whom correspondence should be addressed.
Harm Peters, E-mail: Harm.Peters{at}charite.de



This article has no Abstract. Keywords: cardiac dysrhythmia; local RAS; mast cells; renin.

Basic science article this editorial is based on: Cardiac mast cell-derived renin promotes local angiotensin formation, norepinephrine release and arrhythmias in ischaemia/reperfusion. Mackins CJ, Kano S, Seyedi N et al. J Clin Invest 2006; 116: 1063-1070


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