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NDT Advance Access published online on September 2, 2006
Nephrology Dialysis Transplantation, doi:10.1093/ndt/gfl485
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© The Author [2006]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Received May 30, 2006
Accepted July 20, 2006

Translational Nephrology

Dynamics at the slit diaphragm--is nephrin actin'?

Marcus J. Moeller 1 *

1 RWTH Aachen, Division of Nephrology, Internal Medicine 2, Pauwelsstr. 30, 52074 Aachen, Germany

* To whom correspondence should be addressed.
Marcus J. Moeller, E-mail: mmoeller{at}ukaachen.de



This article has no Abstract. Keywords: actin; FAT1; foot process; Nck; nephrin; podocyte.

Comment on Verma R, Kovari I, Soofi A, Nihalani D, Patrie K, Holzman LB. Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization. J Clin Invest 2006; 116: 1346-1359 and Jones N, Blasutig IM, Eremina V et al. Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes. Nature 2006; 440: 818-823.


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