NDT Advance Access published online on May 25, 2004
Nephrology Dialysis Transplantation, doi:10.1093/ndt/gfh130
© 2004 by European Renal Association - European Dialysis and Transplant Association
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1 Psychonephrology Study Group, Institute of Behavioral Sciences, Budapest, ;1st Department of Internal Medicine, Semmelweis University Budapest, Budapest, Hungary;Department of Medicine, Faculty of Medicine, Canada
* To whom correspondence should be addressed. E-mail: mucsist{at}net.sote.hu.
Background. The prevalence of sleep problems (insomnia, restless legs syndrome, periodic limb movements in sleep and sleep apnoea) has been shown to be high in patients with end-stage renal disease (ESRD) and might contribute to impaired quality of life in this population. Methods. In a cross-sectional study using self-administered questionnaires, we examined the prevalence of sleep disorders and assessed their effect on different aspects of health-related quality of life in a sample of Hungarian patients on maintenance dialysis. Results. Our data confirm that sleep problems are frequent in patients with ESRD; 65% of the patients reported symptoms of at least one specific sleep disorder; insomnia was the most common sleep complaint with 49%, the prevalence of sleep apnoea was 32% and the prevalence of restless legs syndrome was 15%. Co-morbidity, assessed by the End-Stage Renal Disease Severity Index, was shown to be an independent predictor of sleep disorders. Patients with sleep disorders reported higher illness intrusiveness and worse self-perceived health than those without sleep problems. The presence of sleep disorders was an independent predictor of illness intrusiveness, an important determinant of health-related quality of life. Conclusion. Sleep disorders are important determinants of illness intrusiveness and health-related quality of life in patients with ESRD. Sleep problems may be treated successfully; therefore, more attention should be paid to assessing these problems in this patient population.
Accepted December 19, 2003
Original Article
Sleep disorders and illness intrusiveness in patients on chronic dialysis
2 Psychonephrology Study Group, Institute of Behavioral Sciences, Budapest; 2nd Department of Internal Medicine, St Margaret Hospital, Budapest, Hungary
3 Psychonephrology Study Group, Institute of Behavioral Sciences, Budapest, Hungary
4 Nephrocentrum Foundation, Budapest, Hungary
5 Psychonephrology Study Group, Institute of Behavioral Sciences, Budapest, Quintiles Hungary Ltd, Budapest, Hungary
6 1st Department of Internal Medicine, Semmelweis University Budapest, Budapest, Hungary
7 Psychonephrology Study Group, Institute of Behavioral Sciences, Budapest, Hungary;Sleep Research Laboratory, Department of Psychiatry, University Health Network, University of Toronto, Canada
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