NDT Advance Access originally published online on October 12, 2007
Nephrology Dialysis Transplantation 2008 23(1):385-386; doi:10.1093/ndt/gfm701
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© The Author [2007]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org
Diffuse alveolar haemorrhage in a systemic lupus erythematosus patient successfully treated with rituximab: a case report
1Universitätsklinikum Bonn, Medizinische Klinik und Poliklinik I – Allgemeine Innere Medizin, Sigmund-Freud-Str. 25, D-53127 Bonn, Germany and 2Praxis für Nieren- und Hochdruckkrankheiten, Rheinstr. 37, 53179 Bonn, Germany
Correspondence and offprint requests to: Cordula M. Nellessen, Department of Medicine I, University of Bonn, Sigmund-Freud-Str. 25, 53105 Bonn, Germany. Tel: +49-228-287-15507; Fax: +49-228-28714322; E-mail: cordula.nellessen@ukb.uni-bonn.de
Keywords: diffuse alveolar haemorrhage; rituximab; systemic lupus erythematosus
| The first 10% of the full text of this article appears below. |
| Introduction |
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Diffuse alveolar haemorrhage (DAH) often mimics, clinically and radiologically, severe pneumonia or ARDS [1]. The causes of DAH include a variety of non-infectious diseases, e.g. collagen vascular disease. In DAH associated with SLE, a regimen of corticosteroids combined with cyclophosphamide and plasma exchange is generally recommended [2]. We describe here a ventilated SLE patient with DAH refractory to standard therapies. To our knowledge, this represents the first successful application of rituximab in DAH.
| Case report |
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A 29-year-old North African female presented to our institution
| Discussion |
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This article has been cited by other articles:
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D. Todd and K. Costenbader Dyspnoea in a young woman with active systemic lupus erythematosus Lupus, August 1, 2009; 18(9): 777 - 784. [Abstract] [PDF] |
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