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Nephrology Dialysis Transplantation 2007 22(Supplement 7):vii69-vii77; doi:10.1093/ndt/gfm331
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© The Author [2007]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Haemodialysis dose and serum bicarbonate (Chapter 7)

Charlie Tomson1, David Thomas2, Raman Rao1, Dirk van Schalkwyk1 and David Ansell1

1UK Renal Registry, Bristol and 2Department of Renal Medicine, University Hospital of Wales

Correspondence and offprint requests to: Charlie Tomson, UK Renal Registry, Bristol. Email: charlie.tomson{at}nbt.nhs.uk



  Abstract

Data from 21 renal units was insufficient to allow analyses of the dose of dialysis in those units. Amongst the remainder, there is evidence of a progressive increase in the proportion of patients meeting the Renal Association audit standard for urea reduction ratio (URR).

In the UK as a whole, 81% of prevalent haemodialysis patients met the standard for URR in 2005. Greater achievement of the standard in a given unit is associated with a higher median URR in that unit, although there is some evidence that some units have been able to narrow the distribution of achieved URR values.

Achievement of the standard remains, as in previous years’ Reports, less common amongst patients recently established on haemodialysis compared with those established on haemodialysis for longer.

Correction of acidosis, as measured by serum bicarbonate concentration remains highly variable, although there is continued uncertainty about the interpretation of routine measurements of venous serum bicarbonate concentration in haemodialysis patients.

Overall, ~64% of UK haemodialysis patients, and 50% of peritoneal dialysis patients met the Renal Association standard for serum bicarbonate in 2005.


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