NDT Advance Access originally published online on April 1, 2007
Nephrology Dialysis Transplantation 2007 22(6):1769-1771; doi:10.1093/ndt/gfm034
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© The Author [2007]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Retinal arterial and venous occlusions in patients with ADPKD

1Division of Nephrology and Hypertension and 2Department of Physiology and Biomedical Engineering,
Department of Ophthalmology, Mayo Clinic College of Medicine and Mayo Graduate School, Rochester, MN, USA
Correspondence and offprint requests to: Qi Qian, Assistant Professor of Medicine and Physiology, Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA. Email: qian.qi@mayo.edu
Keywords: ADPKD; central retinal vascular occlusion; hypertension; vasculopathy
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| Introduction |
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Autosomal dominant polycystic kidney disease (ADPKD) is a systemic disease with renal and extra renal, cystic and non-cystic manifestations. The cystic disease involves kidney, liver, pancreas, seminal vesicles and meninges. Non-cystic manifestations include aneurysms and dolichoectasias (intracranial, thoracic aorta, coronary and other arteries), valvular heart disease, hernias and possibly intestinal diverticula [1]. Hypertension, arterial vasospasm, and extensive remodelling of small renal arteries and arterioles at early stages of cystic disease are also evident [25]. Cardiovascular complications are the leading cause of death in ADPKD. Here, we report eight cases of retinal arterial and/or venous occlusions in patients with ADPKD and propose that these conditions may be part of the generalized vasculopathy
| Case report |
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| Discussion |
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