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NDT Advance Access originally published online on February 3, 2007
Nephrology Dialysis Transplantation 2007 22(4):1233-1235; doi:10.1093/ndt/gfl841
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© The Author [2007]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Linear anti-glomerular basement membrane IgG but no glomerular disease: Goodpasture's syndrome restricted to the lung

Sanjeev Sethi1, Matthew Lewin1, Lauren Lopez2 and Donna Lager1

1Department of Laboratory Medicine and Pathology, Mayo Clinic, 55905 Rochester, MN and 2Department of Medicine, Elmbrook Memorial Hospital, Brookfield, WI, USA

Correspondence and offprint requests to: Sanjeev Sethi, MD, PhD, Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA. Email: sethi.sanjeev@mayo.edu

Keywords: goodpasture's syndrome; anti-GBM antibodies; IgG4

The first 10% of the full text of this article appears below.



   Introduction
 
We present an unusual case of Goodpasture's syndrome with pulmonary manifestations and no renal function abnormalities and normal urinalysis, although there was intense linear staining for anti-glomerular basement membrane (GBM) antibodies.



   Case presentation
 
C.V. is a 22-year-old woman, who presented to the emergency room (ER) with shortness of breath, coughing and frank haemoptysis. She had been seen in the ER twice over the previous 3 weeks for similar symptoms, but with only mild blood-tinged sputum. Chest X-ray showed bilateral infiltrates. She was treated with Zithromax and subsequently Biaxin for a presumed pneumonia. There was no history of fevers, chills or weight loss. However, the haemoptysis . . . [Full Text of this Article]



   Renal biopsy findings
 
Renal biopsy diagnosis


   Clinical follow-up
 


   Discussion
 

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