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NDT Advance Access originally published online on November 26, 2007
Nephrology Dialysis Transplantation 2007 22(12):3377-3380; doi:10.1093/ndt/gfm508
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© The Author [2007]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org


Towards the prevention of bone fractures in dialysed patients?

Michel Jadoul

Cliniques Universitaires St. Luc, Université Catholique de Louvain, B-1200 Brussels, Belgium

Correspondence to: Prof. M. Jadoul, Cliniques Universitaires, St. LUC, Université, Catholique de Louvain, B-1200 Brussels, Belgium. Email: jadoul@nefr.ucl.ac.be

Keywords: epidemiology; fall; fracture; hemodialysis; prevention

The first 150 words of the full text of this article appear below.



   Epidemiology of bone fractures in dialysed patients
 
Incidence
Alem et al. [1] have compared the incidence of hip fractures in US dialysis patients [based on United States Renal Data System (USRDS) Registry data] with that of the general population, based on data from Olmstead County (Minnesota). They report a four times higher incidence in dialysed patients matched for age, gender and race (the study being limited to Caucasians).

Very recently, the incidence of hip fractures and all fractures has been studied in the 12 countries of the Dialysis Outcomes and Practice Patterns Study (DOPPS, phase 2). The yearly incidence is 0.89% for hip fractures and 2.6% for all fractures (for a mean age around 60 years), without major differences between countries after adjustment for demographics and comorbidity [2]. This study extends to the worldwide haemodialysis (HD) community the evidence of a much higher incidence of hip fracture in HD patients than in the general . . . [Full Text of this Article]

Risk factors
Prognostic impact and costs


   Why is the fracture risk increased in HD patients?
 


   Is there a place for measuring bone density and treating osteoporosis in HD patients?
 


   Potential strategies to prevent fractures in dialysed patients
 

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