NDT Advance Access originally published online on July 10, 2007
Nephrology Dialysis Transplantation 2007 22(11):3322-3326; doi:10.1093/ndt/gfm431
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© The Author [2007]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Dengue haemorrhagic fever-induced acute kidney injury without hypotension, haemolysis or rhabdomyolysis
1Division of Nephrology, Hospital de Base and 2Laboratory of Virology, Division of Infectious Diseases, São José do Rio Preto Medical School, Brazil
Correspondence and offprint requests to: E. A. Burdmann, Av. Brigadeiro Faria Lima 5416, Sao Jose do Rio Preto, SP, Brazil, 15090-000. Email: burdmann@famerp.br
Keywords: acute kidney injury; acute renal failure; dengue; dengue haemorrhagic fever; proteinuria
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| Introduction |
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Dengue fever (DF) is currently the most important human viral mosquito-borne infection of public health significance, with millions of infections each year. The main dengue vector is the female of the Aedes aegypti mosquito. There are four serotypes of the dengue virus (DEN-1–DEN-4), a RNA flavivirus. They are antigenically closely related, but whereas infection with one serotype produces lifelong immunity to that serotype, immunity to other serotypes lasts only a few months [1,2].
Approximately half the world's population lives in areas potentially at risk for dengue and 50–100 million cases are estimated to occur annually [1,3]. Brazil is the leading American country in absolute number of cases and has the highest incidence rate of the disease in this geographic area [4]. The epidemiology of dengue in Brazil comprised two distinct periods. In the first (1986–1993), epidemic waves occurred in localized
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| Discussion |
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