Skip Navigation


NDT Advance Access originally published online on June 27, 2007
Nephrology Dialysis Transplantation 2007 22(11):3304-3310; doi:10.1093/ndt/gfm345
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
22/11/3304    most recent
gfm345v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Guida, B.
Right arrow Articles by Sabbatini, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Guida, B.
Right arrow Articles by Sabbatini, M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author [2007]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org


Role of dietary intervention on metabolic abnormalities and nutritional status after renal transplantation

Bruna Guida1, Rossella Trio1, Roberta Laccetti1, Annamaria Nastasi1, Elena Salvi1, Nunzia Ruggiero Perrino1, Carmela Caputo2, Eliana Rotaia2, Stefano Federico2 and Massimo Sabbatini2

1Department of Neuroscience, Physiology Nutrition Unit and 2Division of Nephrology, University Federico II, Naples, Italy

Correspondence and offprint requests to: Bruna Guida, Department of Physiology, Faculty of Medicine, University ‘Federico II’ of Naples, Via Tasso 91/B 80100 Napoli, Italy. Email: bguida{at}unina.it



  Abstract

Background. In these last years, several traditional risk factors for cardiovascular disease, like obesity, dyslipidaemia, hypertension and post-transplant diabetes mellitus have been also identified as important non-immunological risk factors leading to the development of chronic allograft nephropathy, the first cause of graft loss in transplanted patients. The aim of the present study was to determine the effects of a 12-month dietary regimen on the nutritional status and metabolic outcome of renal transplant recipients in the first post-transplant year.

Methods. Forty-six cadaver-donor renal transplant recipients (mean age 40.8 ± 10.1-years), enrolled during the first post-transplant year (4.8 ± 3.3 months) and followed prospectively for a 12 month period. Biochemical and nutritional markers, anthropometric measurements, body composition (by conventional bioelectrical impedance analysis) and dietary records (using a detailed food-frequency questionnaire) at baseline and after 12 months.

Results. Compliance to the diet was related to sex (male better than female) and was associated with weight loss primarily due to a decrease in fat mass, with decrease in total cholesterol and glucose plasma levels and with a concomitant rise in serum albumin.

Conclusion. After renal transplantation, health benefits of proper metabolic balance that include reduced body fat, weight loss, lower cholesterol and triglycerides levels and an improvement, fasting glucose levels can be obtained when dietary intervention occurred.

Keywords: bioelectrical impedance analysis; dietary intervention; metabolic abnormalities; nutritional status; renal transplantation

Received for publication: 6.12.06
Accepted in revised form: 4. 5.07


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.