NDT Advance Access originally published online on October 18, 2006
Nephrology Dialysis Transplantation 2007 22(1):53-58; doi:10.1093/ndt/gfl601
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© The Author [2006]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Cardiovascular disease in haemodialysis and peritoneal dialysis: arguments pro peritoneal dialysis
Renal Division, Department of Internal Medicine, University Hospital Ghent, Belgium
Correspondence and offprint requests to: W. Van Biesen, Renal division, Department of Internal Medicine, University Hospital Ghent, De Pintelaan 185, 9000 Ghent, Belgium. Email: wim.vanbiesen@urgent.be
Keywords: cardiovascular; hemodialysis; outcome; peritoneal dialysis; survival; uraemic toxins
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| Introduction |
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Cardiovascular disease is frequent in end-stage renal disease (ESRD) patients, and it is the major cause of morbidity [1,2] and mortality [3] in this population. It can manifest itself as ischaemic heart disease, congestive heart failure, atherosclerotic peripheral vascular disease [4] or cerebrovascular disease [5]. In the last decade, evidence has accrued that part of this cardiovascular damage might be due to renal replacement therapy (RRT) itself, and the question whether haemodialysis (HD) or peritoneal dialysis (PD) is more harmful than the other is, therefore, of high relevance.
Some recent publications have suggested a worse outcome in PD as compared with HD patients [6,7] with congestive heart failure or coronary heart disease, pleading to avoid PD in cardiovascular-compromised patients. Are these results the confirmation that PD is a second-class treatment, or are we listening to the
Clinical outcome studies
General population studies
Dialysis modality and de novo cardiac disease
Patients with existing cardiovascular disease
Causes of cardiovascular risk in ESRD patients, performance differences between different modes of PD and HD and their relation to impact on cardiovascular outcome
Uraemic retention products, modality and cardiovascular outcome
Volume status, modality and cardiovascular outcome
Inflammation, modality and cardiovascular risk
Traditional cardiovascular risk factors in PD and HD
| Conclusions |
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This article has been cited by other articles:
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M. Krajewska, W. Kosmala, W. Weyde, K. Madziarska, T. Porazko, W. Kopec, R. Klak, J. Penar, M. Kusztal, E. Watorek, et al. The effect of dialysis modality (PD and HD) on cardiac morphology and functions in chronic kidney disease patients at very high cardiovascular risk Nephrol. Dial. Transplant., February 1, 2008; 23(2): 768 - 769. [Full Text] [PDF] |
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