NDT Advance Access originally published online on April 20, 2006
Nephrology Dialysis Transplantation 2006 21(9):2647-2649; doi:10.1093/ndt/gfl153
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© The Author [2006]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Case Report
Improvement in open-angle glaucoma by nocturnal home haemodialysis
1 Department of Medicine, Division of Nephrology, Akdeniz University School of Medicine Hospital,Antalya, Turkey and 2 Department of Medicine, Division of Nephrology, Toronto General Hospital University Health Network, University of Toronto, Toronto, Canada
Correspondence and offprint requests to: Dr Christopher T. Chan, Toronto General Hospital University Health Network, 200 Elizabeth Street, North Wing 8842, Toronto, ON, Canada M5G 2C4. Email: christopher.chan@uhn.on.ca
Keywords: glaucoma; intra-ocular pressure; nocturnal haemodialysis
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| Introduction |
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Open-angle glaucoma (OAG) is a common ocular abnormality seen in patients with end-stage renal disease (ESRD) [1]. Although the pathogenesis of OAG is not yet fully understood, lowering intraocular pressure is the accepted treatment goal. Without adequate treatment, glaucoma can lead to visual disability and eventual blindness [2].
From a simplified viewpoint, intraocular pressure is determined by the balance between aqueous production from the ciliary body and drainage of the aqueous humour through the trabecular meshwork. Normal intraocular pressure (IOP) ranges from 10 to 21 mmHg. IOP of 2030 mmHg usually results in chronic optic nerve damage. In cases of significant intraocular hypertension (4050 mmHg), rapid visual loss and retinovascular occlusion may occur.
Intradialytic alteration of IOP by conventional haemodialysis (CHD) has
| Case history |
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| Discussion |
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