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NDT Advance Access originally published online on May 30, 2006
Nephrology Dialysis Transplantation 2006 21(8):2296-2300; doi:10.1093/ndt/gfl265
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© The Author [2006]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Technical Note

Continuous renal replacement therapy (CRRT) in children using the AQUARIUSTM

Daljit Kaur Hothi1, Cecilia St George-Hyslop2, Denis Geary1, Desmond Bohn2 and Elizabeth Harvey1

1 Division of Nephrology and 2 Pediatric Critical Care Unit, Hospital for Sick Children, Toronto, Canada

Correspondence and offprint requests to: Dr Elizabeth Harvey, Division of Nephrology, Hospital for Sick Children, 555 University Avenue, Toronto, M5G 1X8 Ontario, Canada. Email: elizabeth.harvey@sickkids.ca

Keywords: AQUARIUSTM; continuous renal replacement therapy; children

The first 150 words of the full text of this article appear below.



   Introduction
 
Continuous renal replacement therapy (CRRT) is the preferred choice for blood purification and volume control in critically ill children [1,2]. The reported overall survival rate for children requiring CRRT is 60% [3], and mortality in infants is comparable with that of older children and adolescents [4].

It is imperative in paediatric CRRT that equipment be adaptable to accommodate large variations in size (2–100 kg). Until recently at the Hospital for Sick Children, CRRT was provided using the PRISMATM (Gambro AB, Stockholm, Sweden) circuits designed for adult use. A ‘Hot-LineTM’(Smiths-Level 1 Inc., Rockland, MA) blood warmer prevented hypothermia but increased the extracorporeal circuit volume by 25 ml, which then exceeded 10% of the blood volume for patients weighing <15 kg. The PRISMA M10TM, a 50 ml paediatric circuit, reduced the weight for a blood prime to ≤8 kg, but we elected . . . [Full Text of this Article]



   Methods
 


   Results
 


   Discussion
 
Benefits
(1) Hypothermia
(2) and (3) TMP alarms and minimum substitution fluid rate
(4) Balance alarms
(5) Negative ‘pressure drop’
(6) Recurrent clots
(7) Single substitution fluid weighing scale
(8) Post-dilutional CVVHDF
(9) Return-pressure-sensor leak
(10) Master keyboard failure


   Conclusion
 

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