NDT Advance Access originally published online on August 25, 2006
Nephrology Dialysis Transplantation 2006 21(12):3567-3570; doi:10.1093/ndt/gfl496
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© The Author [2006]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Intra-abdominal hypertension is an under-appreciated cause of acute renal failure
1Department of Nephrology and Endocrinology, The University of Tokyo Hospital, Tokyo, Japan, 2Division of Nephrology and Hypertension and 3Department of Medicine, Oregon Health & Science University, Portland, Oregon, USA
Correspondence and offprint requests to: Ihab Wahba, MD, Division of Nephrology and Hypertension, Oregon Health & Science University, 3314 SW US Veterans Hospital Road, PP 262, Portland, OR 97239, USA. Email: wahbai@ohsu.edu
Keywords: abdominal compartment syndrome; acute renal failure; intra-abdominal hypertension; intra-abdominal pressure; oliguria
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Increased intra-abdominal pressure (IAP), known as intra-abdominal hypertension (IAH) is increasingly being recognized as an important predictor of adverse outcomes in critically ill patients. The prevalence of IAH has recently been estimated at between 32 and 65% in both medical and surgical intensive care units [12]. High grade IAH may result in abdominal compartment syndrome (ACS), where increased pressure in a closed anatomic space threatens the viability of surrounding tissues and organs [1,2]. Renal dysfunction is one of the earliest and most common presentations in ACS. As IAP increases, glomerular filtration rate (GFR) decreases progressively and anuria may ensue [3,4]. Cases of acute renal failure (ARF) quickly reversed by abdominal decompression (DC) have been well-documented in the surgical literature [3], but surprisingly, only a handful of cases were reported in the nephrology literature [4]. Even
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| Case series |
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Case 1
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