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NDT Advance Access originally published online on May 26, 2005
Nephrology Dialysis Transplantation 2005 20(8):1726-1728; doi:10.1093/ndt/gfh910
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© The Author [2005]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org

Case Report

Steroid-responsive focal segmental glomerulosclerosis in primary antiphospholipid syndrome with successful pregnancy outcome

Dipankar Bhowmik1, Vatsala Dadhwal2, Amit K. Dinda3, Rohini Handa4 and Suresh C. Dash1

1 Department of Nephrology, 2 Department of Obstetrics and Gynecology, 3 Department of Pathology and 4 Department of Medicine, All India Institute of Medical Sciences, New Delhi, India

Correspondence and offprint requests to: Dr Dipankar Bhowmik, Department of Nephrology, All India Institute of Medical Sciences, New Delhi-110029, India. Email: dbhowmik@aiims.ac.in

Keywords: focal segmental glomerulosclerosis; pregnancy; primary antiphospholipid syndrome

The first 150 words of the full text of this article appear below.



   Introduction
 
Antiphospholipid syndrome (APS) is a clinico-pathological syndrome characterized by the association of venous and/or arterial thrombo-embolic events, pregnancy morbidity and the presence of circulating antiphospholipid (APL) antibodies, namely lupus anticoagulant (LA) and/or anticardiolipin antibodies (ACLs). The diagnosis of definite APS is made when the patient fulfils one clinical (thrombosis or pregnancy morbidity) and one laboratory (APL or LA) criterion [1]. APS may be primary or secondary to various autoimmune diseases: systemic lupus erythematosus (SLE), rheumatoid arthritis and systemic sclerosis. The commonly described renal involvement in APS includes renal artery stenosis and/or thrombosis, renal infarction, renal vein thrombosis and thrombotic microangiopathy [2]. In the last few years, glomerular involvement has been documented [3,4]. We report a case of primary APS with nephritic syndrome due to focal segmental glomerulosclerosis (FSGS), and a successful pregnancy outcome.



   Case
 
A 31-year-old female was referred 4 years previously by . . . [Full Text of this Article]



   Discussion
 

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