Skip Navigation


NDT Advance Access originally published online on February 16, 2005
Nephrology Dialysis Transplantation 2005 20(6):1263-1266; doi:10.1093/ndt/gfh724
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
20/6/1263    most recent
gfh724v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (1)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Charney, D. A.
Right arrow Articles by Aron, N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Charney, D. A.
Right arrow Articles by Aron, N.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author [2005]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org

Teaching Point
(Section Editor: Alain Meyrier)

Supported by an educational grant from {genzyme}

A male nephrotic patient with rapid decline of renal function

Douglas A. Charney1, Ashutosh Singh2 and Narcis Aron2

1 Department of Pathology and 2 Department of Internal Medicine, Nephrology Division, St Luke's-Roosevelt Hospital Center, New York, NY, USA

Correspondence and offprint requests to: Douglas A. Charney, MD, St Luke's Hospital, Department of Pathology, Clark 4, 1111 Amsterdam Avenue, New York, NY 10025, USA. Email: dcharney@chpnet.org

Keywords: crescent; fibrin crescent; membranous nephropathy

The first 10% of the full text of this article appears below.



   Case
 
A 56-year-old African American male presented to the emergency room after 2 weeks of gradually worsening dyspnoea, cough, periorbital and lower extremity oedema, a 20 lb weight gain and dark coloured urine. The patient had a history of hypertension and hypercholesterolaemia, and had been treated with hydrochlorothiazide, lisinopril and atorvastatin.

Three months previously, his blood urea nitrogen (BUN) was 22 mg/dl (7.8 mmol/l), serum creatinine was 1.3 mg/dl (115 µmol/l) and urinalysis showed 3+ proteinuria by dipstick.

Currently, his physical examination revealed a blood pressure of 177/125 mmHg and periorbital and 3+ lower extremity oedema. Initial abnormal laboratory data included BUN of 47 mg/dl, serum creatinine of 3.5 mg/dl, albumin of 1.2 gm/dl, cholesterol of 348 mg/dl, triglycerides of 252 mg/dl and serum creatine kinase of 783 U/l. Blood cell counts . . . [Full Text of this Article]



   Discussion
 


   Teaching points
 

Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?