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Case Report
Haemorrhagic Campylobacter jejuni and CMV colitis in a renal transplant recipient
1 Department of Nephrology, 2 University of Melbourne, Department of Medicine and 3 Department of Anatomical Pathology, St. Vincent's Hospital, Melbourne, Australia
Correspondence and offprint requests to: Dr Nigel Toussaint, Department of Nephrology, St. Vincent's Hospital, PO Box 2900, Fitzroy, Victoria 3065, Australia. Email: Nigel.Toussaint@mh.org.au
Keywords: Campylobacter infections; colitis; cytomegalovirus infections; kidney transplantation
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| Introduction |
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Cytomegalovirus (CMV) infection is a significant cause of morbidity and mortality in recipients of all organ transplants. The reported incidence of CMV infection and disease is varied, the wide range related to differences in methods of detection and in immunosuppression protocols. Nonetheless, evidence of active CMV disease can be found in up to two-thirds of patients following renal transplantation [1].
CMV infection can involve a number of organs, including the gastrointestinal tract (GIT), with a clinical presentation of abdominal pain, diarrhoea, haematochezia and constitutional symptoms, such as fever, malaise and weight loss. The factors that predispose the colon to CMV infection are unknown [2]. The virus has a tendency to infect tissues with a high cell turnover and, therefore, CMV infection may localize to the GIT mucosa in areas of inflammation. We report a case of severe necrotizing colitis related to CMV infection in a renal
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