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Nephrology Dialysis Transplantation 2005 20(4):817-819; doi:10.1093/ndt/gfh659
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© The Author [2005]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org


Case Report

‘Primary’ nephrosclerosis in a type 1 diabetic patient

Manuel Burdese1, Valentina Consiglio1, Elisabetta Mezza1, Daniela Bergamo1, Giorgio Grassi2, Giorgio Soragna1, Maura Rossetti1, Giuseppe Paolo Segoloni1, Gianna Mazzucco3 and Giorgina Barbara Piccoli1

1 Section of Nephrology, Department of Internal Medicine, 3 Dipartimento di Scienze Cliniche e Biologiche, University of Turin and 2 SC Diabetology–ASO ‘S.Giovanni Battista’, Turin, Italy

Correspondence and offprint requests to: Giorgina Barbara Piccoli, MD, Section of Nephrology of the University of Turin, Corso Bramante 86–88, 10126 Torino, Italy. Email: gbpiccoli@yahoo.it or giorgina.piccoli@unito.it

Keywords: diabetes mellitus; kidney–pancreas transplantation; nephrosclerosis; pre-emptive transplantation; renal biopsy

The first 10% of the full text of this article appears below.



   Introduction
 
End-stage renal disease is a well known long-term complication of type 1 diabetes. Its diagnosis in typical cases is obvious, and, in non-typical cases, i.e. those lacking the classic hallmark of proteinuria or showing discrepancies between end-organ damage (in particular between nephropathy and retinopathy), a renal biopsy is usually indicated [1]. However, the work-up protocol is tailored for patients referred early to nephrologists. The clinical choice may be less clear, however, in the case of late referral, when the renal disease is advanced and a renal biopsy (displaying the presence of a non-diabetic nephropathy) is probably of minor therapeutic relevance.

The present case report is that of a patient referred late to the nephrologist, who performed a renal biopsy because of an atypical course, during . . . [Full Text of this Article]



   Case
 


   Discussion
 

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