NDT Advance Access originally published online on September 2, 2005
Nephrology Dialysis Transplantation 2005 20(11):2545-2547; doi:10.1093/ndt/gfi071
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© The Author [2005]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Case Report
Massive oedema in a Cape Verde sailor
1 Division of Nephrology, Department of Medicine and 2 Department of Pathology, Academic Medical Centre, Amsterdam, The Netherlands
Correspondence and offprint requests to: Aafke E. de Graaff, Academic Medical Centre, Department of Nephrology, Room Fu-215, Meibeigdreef 9, 1105 A2, Amsterdam. The Netherlands. Email: a.e.degraaff@amc.uva.nl
Keywords: albuminuria; diabetic nephropathy; HHV8; Kaposi sarcoma
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Hypoalbuminaemia, fluid retention and interstitial oedema may seem a straightforward combination in a patient with longstanding poorly regulated diabetes suspected to have diabetic nephropathy, but can constitute a complex diagnostic problem with an unusual therapeutic approach and an unexpected outcome. Here we present a patient with longstanding type II diabetes, mild albuminuria, a biopsy-proven diabetic glomerulopathy and low serum albumin levels, who developed massive fluid retention and oedema during a systemic infection complicated by a sudden skin manifestation of non-human immunodeficiency virus (HIV)-related Kaposi sarcoma. His oedema and hypoalbuminaemia only resolved after treatment of his Kaposi sarcoma.
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A 56-year-old man,
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