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Nephrol Dial Transplant (2004) 19: 1913-1915
Nephrol Dial Transplant Vol. 19 No. 7 © ERA-EDTA 2004; all rights reserved

Case Report

Aristolochic acid nephropathy complicating a patient with focal segmental glomerulosclerosis

Stanley Hok-King Lo1, Ka-Leung Mo1, Kin-Shing Wong1, Suet-Ping Poon2, Ching-Kit Chan1, Chi-Kong Lai3 and Albert Chan3

1 Department of Medicine and 2 Department of Pathology, Pamela Youde Nethersole Eastern Hospital and 3 Department of Pathology, Princess Margaret Hospital, Hong Kong SAR, China

Correspondence and offprint requests to: Stanley Lo, Renal Division, Department of Medicine, Pamela Youde Nethersole Eastern Hospital, 3 Lok Man Road, Chaiwan, Hong Kong SAR, China. Email: stanleylo@alumni.cuhk.net

The first 150 words of the full text of this article appear below.



   Case
 
A 75-year-old Chinese male was admitted to hospital with a 1 week history of ankle oedema, facial puffiness and frothy urine. He had no sore throat, smoky urine, rash, joint pain, fever, night sweat or weight loss. He did not experience shortness of breath. Five weeks before, he was admitted for insidious onset of right-sided weakness with a 1 year history of chronic neck pain after an accidental fall. He was then found to have prostate enlargement with a hard nodule. He had no family history of renal disease. He did not smoke or drink. His blood pressure measured 180/100 mmHg. Clinically, he had ankle oedema and had no lymphadenopathy. Jugular venous pressure was not elevated. His abdomen was soft and non-tender. No organomegaly was found. He had a right pyramidal weakness (power grade: 4 over 5) and hyperreflexia over right-sided limbs. Initial investigation showed features of nephrotic syndrome and . . . [Full Text of this Article]



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