Nephrol Dial Transplant (2004) 19: 1305-1307
Nephrol Dial Transplant Vol. 19 No. 5 © ERA-EDTA 2004; all rights reserved
Case Report
ACTH-induced improvement in the nephrotic syndrome in patients with a variety of diagnoses
1Department of Nephrology, University Hospital, Lund, Sweden and 2Department of Medicine, Landspitali University Hospital Hringbraut, Reykjavik, Iceland
Correspondence and offprint requests to: Anna-Lena Berg, Department of Nephrology, University Hospital, S-221 85 Lund, Sweden. Email: Anna-Lena.Berg@njur.lu.se
Keywords: corticotropin; diabetes nephropathy; glomerulonephritis; nephrotic syndrome; treatment
| The first 10% of the full text of this article appears below. |
 |
Introduction |
|---|
In the fifties and the sixties, ACTH was widely used for the treatment of childhood nephrosis probably caused by minimal change disease in most cases [1,2]. This treatment was provided in lieu of steroids since it does not suppress the adrenal glands and there were hopes of less growth stunting. There are a few reported cases of ACTH treatment in nephrotic patients who had not been biopsied but probably suffered from other diseases than minimal change disease [3,4]. These patients received huge doses of short-acting ACTH for days or weeks and some of then seemed to respond, at least partially. During the last few decades the use of ACTH has been limited due to the fact that the preparation must be given parenterally.
We have reported that treatment with a synthetic ACTH analogue (ACTH1–24;
|
Cases |
|---|
|
Discussion |
|---|
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  F. C. Fervenza, S. Sethi, and U. Specks Idiopathic Membranous Nephropathy: Diagnosis and Treatment Clin. J. Am. Soc. Nephrol., May 1, 2008; 3(3): 905 - 919. [Abstract] [Full Text] [PDF]
|
|