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Nephrol Dial Transplant (2004) 19: 720-722
Nephrol Dial Transplant Vol. 19 No. 3 (c) ERA-EDTA 2004; all rights reserved

Case Report

Stonemason's systemic vasculitis: three cases and a dilemma

John Main and Caroline Wroe

The James Cook University Hospital, Middlesbrough, UK

Correspondence and offprint requests to: Dr A. C. Wroe, SpR Nephrology, The James Cook University Hospital, Marton Road, Middlesbrough TS4 3BW, UK. Email: carolinewroe@blueyonder.co.uk

Keywords: silica; stonemasons; systemic vasculitis

The first 10% of the full text of this article appears below.



   Introduction
 
There is an established link between silica exposure and the development of systemic vasculitis. There is no clear quantification of the risk of exposure, or how to protect workers against it. We report three cases of systemic vasculitis from similar workplaces and a dilemma relating to the son of one of the cases.



   Case 1
 
A 37-year-old man presented to his GP in July 1987 complaining of a 1-month history of a blocked nose and oral ulceration. He had worked as a quarryman for several years, often in the same quarry as cases 2 and 3. During this time, he was exposed to dust from silica-rich sandstone. A nasal biopsy showed ulceration consistent with Wegener's granulomatosis. He had dipstick haematuria and proteinuria. cANCA was positive at 1:80; serum urea and creatinine were . . . [Full Text of this Article]



   Case 2
 


   Case 3
 


   Case 4
 


   Discussion
 

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