Nephrol Dial Transplant (2004) 19: 511-512
© ERAEDTA 2004; all rights reserved
Letter
Albumin and glomerular permselectivity
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Sir,
We note with interest the recent commentary entitled What is the role of albumin in proteinuric glomerulopathies by B. Rippe [1] whose content is closely related to our paper. It is important to bring to the attention of the reader that there are other publications in the literature, which would not support the views expressed by Rippe.
The underpinning concept for Rippe's views on glomerular permselectivity and renal handling of albumin is that there exist endothelial sieve plugs made up
1Department of Biochemistry and Molecular Biology Monash University 2Nephrology Section Department of Medicine Monash Medical Centre Clayton Victoria Australia Email: wayne.comper@med.monash.edu.au
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