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Nephrol Dial Transplant (2004) 19: 511-512
© ERA–EDTA 2004; all rights reserved


Letter

Albumin and glomerular permselectivity

The first 10% of the full text of this article appears below.

Sir,

We note with interest the recent commentary entitled ‘What is the role of albumin in proteinuric glomerulopathies’ by B. Rippe [1] whose content is closely related to our paper. It is important to bring to the attention of the reader that there are other publications in the literature, which would not support the views expressed by Rippe.

The underpinning concept for Rippe's views on glomerular permselectivity and renal handling of albumin is that there exist endothelial ‘sieve plugs’ made up . . . [Full Text of this Article]

Tanya M. Osicka1, Kimberley J. Strong1, David J. Nikolic-Paterson2, Robert C. Atkins2 and Wayne D. Comper1

1Department of Biochemistry and Molecular Biology Monash University 2Nephrology Section Department of Medicine Monash Medical Centre Clayton Victoria Australia Email: wayne.comper@med.monash.edu.au


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