Nephrol Dial Transplant (2004) 19: 486-490
© ERAEDTA 2004; all rights reserved
Case Report
Granulomatous interstitial nephritis of the allograft kidney associated with rhodococcal pulmonary infection
Nephrology Division, 1Department of Medicine, 2Department of Microbiology and 3Department of Pathology, Queen Mary Hospital, University of Hong Kong, Hong Kong, China
Correspondence and offprint reequests to: Prof. Kar Neng Lai, Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, China. Email: knlai@hku.hk
Keywords: granulomatous interstitial nephritis; lung abscess; renal transplantation; Rhodococcus equi
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| Introduction |
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Rhodococcus is an aerobic mycobacterium-like coccobacillus that is an usual pathogen in animals, but may also cause opportunistic infection in immunocompromised hosts. Among renal transplant patients, pulmonary infection in the form of cavitating lung abscesses and empyema is most frequently seen, but osteomyelitis, pericarditis, lymphadenitis and recurrent skin infections have also been reported [13]. We recently have encountered a renal allograft recipient presenting with an unusual renal complication of rhodococcal pulmonary infection.
| Case |
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A 52-year-old woman had end-stage renal failure with an unknown aetiology. Although the exact cause could not be identified at presentation, there were no elements suggesting interstitial nephritis as the primary cause of renal failure. Continuous ambulatory peritoneal dialysis was started in 1987, but it was complicated by repeated bacterial peritonitis resulting in ultrafiltration failure which eventually required conversion to long-term haemodialysis in July 1998. Past health was unremarkable apart from an episode of
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