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Nephrol Dial Transplant (2004) 19: 486-490
© ERA–EDTA 2004; all rights reserved


Case Report

Granulomatous interstitial nephritis of the allograft kidney associated with rhodococcal pulmonary infection

Kai Chung Tse1, Tak Mao Chan1, Samson Sai-Yin Wong2, Kwok Wah Chan3, Man Fai Lam1, Kingsley Hau-Ngai Chan1, Fu Keung Li1, Bo Ying Choy1 and Kar Neng Lai1

Nephrology Division, 1Department of Medicine, 2Department of Microbiology and 3Department of Pathology, Queen Mary Hospital, University of Hong Kong, Hong Kong, China

Correspondence and offprint reequests to: Prof. Kar Neng Lai, Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, China. Email: knlai@hku.hk

Keywords: granulomatous interstitial nephritis; lung abscess; renal transplantation; Rhodococcus equi

The first 150 words of the full text of this article appear below.



   Introduction
 
Rhodococcus is an aerobic mycobacterium-like coccobacillus that is an usual pathogen in animals, but may also cause opportunistic infection in immunocompromised hosts. Among renal transplant patients, pulmonary infection in the form of cavitating lung abscesses and empyema is most frequently seen, but osteomyelitis, pericarditis, lymphadenitis and recurrent skin infections have also been reported [1–3]. We recently have encountered a renal allograft recipient presenting with an unusual renal complication of rhodococcal pulmonary infection.



   Case
 
A 52-year-old woman had end-stage renal failure with an unknown aetiology. Although the exact cause could not be identified at presentation, there were no elements suggesting interstitial nephritis as the primary cause of renal failure. Continuous ambulatory peritoneal dialysis was started in 1987, but it was complicated by repeated bacterial peritonitis resulting in ultrafiltration failure which eventually required conversion to long-term haemodialysis in July 1998. Past health was unremarkable apart from an episode of . . . [Full Text of this Article]



   Discussion
 

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