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Nephrol Dial Transplant (2004) 19: 482-485
© 2004 European Renal Association–European Dialysis and Transplant Association

Case Report

Nephrotic range proteinuria in a renal transplant associated with oncocytoma of the native kidney

Michael Lian1, William Mulley1, Kathleen Kan1, Duncan MacGregor2, Andrew Tosolini1 and Francesco Ierino1

1Department of Nephrology and 2Department of Anatomical Pathology, Austin Health, Victoria, Australia

Correspondence and offprint requests to: Dr Francesco Ierino, Department of Nephrology, Austin Health, Studley Road, Heidelberg 3084, Victoria, Australia. Email: frank.ierino@armc.org.au

Keywords: membranous glomerulonephritis; oncocytoma; proteinuria; renal transplant

The first 150 words of the full text of this article appear below.



   Introduction
 
Membranous glomerulonephritis (MGN) is known to cause post-transplant nephrotic syndrome and may be recurrent or de novo [1,2]. Focal glomerulosclerosis (FGS) may also present with nephrotic range proteinuria and has a high incidence of recurrence post-transplantation (20–40%) and approximately half of these recurrences may lead to allograft failure. The risk of recurrent MGN has been reported to be 29% at 3 years and it appears to be more common than de novo MGN in transplant recipients [2, 3]. Schwartz et al. [2] have reported that de novo MGN may occur in 5.3% of patients at 8 years. Although nephrotic syndrome is known to complicate underlying malignancies in the non-transplant setting, the association between nephrotic range proteinuria and tumours following renal transplantation is less well defined. This case report addresses the possible mechanisms of proteinuria in a patient with simultaneous recurrent . . . [Full Text of this Article]



   Case
 


   Discussion
 

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