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Nephrol Dial Transplant (2004) 19: 477-478
© 2004 European Renal Association–European Dialysis and Transplant Association

Case Report

Nephrotic syndrome: cause of an abnormal response to the rapid ACTH stimulation test

Aoife Brennan, Kieran A. O'Connor, William D. Plant and Domhnaill J. O'Halloran

Cork University Hospital, Wilton, Cork, Ireland

Correspondence and offprint requests to: Aoife Brennan, Cork University Hospital, Wilton, Cork, Ireland. Email: itsaoife@eircom.net

Keywords: hypoadrenalism; nephrotic syndrome; rapid ACTH stimulation test

The first 10% of the full text of this article appears below.



   Introduction
 
The intravenous rapid ACTH (250 mcg) stimulation test [short synacten® test (SST)] is the investigation of choice in suspected hypoadrenalism. We describe a patient with nephrotic syndrome in whom the initial SST was abnormal due to low cortisol binding globulin (CBG). Repeat testing, after the patient had developed end-stage renal failure, revealed a normal response.



   Case
 
A 53-year-old woman presented with peripheral oedema. Nephrotic syndrome was diagnosed on the basis of hypoalbuminaemia, proteinuria and dyslipidaemia. She had . . . [Full Text of this Article]



   Discussion
 

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