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Nephrology Dialysis Transplantation 2004 19(10):2683-2685; doi:10.1093/ndt/gfh372
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Nephrol Dial Transplant Vol. 19 No. 10 © ERA-EDTA 2004; all rights reserved

Letter

Non-oliguric acute renal failure and abortion induced by metamizol overdose

The first 10% of the full text of this article appears below.

Sir,

Metamizol is a non-narcotic, analgesic and anti-pyretic pyrazolone derivative which belongs to the non-steroidal anti-inflammatory class of drugs. This drug is used in Germany, Spain and Italy, and in many South American countries. It is prohibited in other countries because of its capacity to induce agranulocytosis and aplastic anaemia. In addition to its effects on bone marrow, metamizol may also cause cutaneous reactions, allergic idiosyncratic reactions such a bronchospasm, anaphylactic shock, toxic epidermal necrolysis, hepatitis and severe hypotension [1]. We report here a case of non-oliguric acute renal failure and abortion following the ingestion of an overdose of . . . [Full Text of this Article]

Ramón Peces1 and Antonio Pedrajas2

1 Sección de Nefrología and2 Servicio de Medicina Interna Hospital General La Mancha-Centro Alcázar de San Juan Ciudad Real Spain E-mail: cpeces@varnet.com


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