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Nephrology Dialysis Transplantation 2004 19(10):2639-2641; doi:10.1093/ndt/gfh345
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Nephrol Dial Transplant Vol. 19 No. 10 © ERA-EDTA 2004; all rights reserved

Case Report

Focal segmental glomerulosclerosis in a girl with myelodysplastic syndrome

Masashi Nishida1, Hiroyuki Ishida3, Noriko Nakai3, Akira Morimoto2, Shinsaku Imashuku4, Kenji Hamaoka1 and Takao Yoshihara3

1 Department of Pediatric Cardiology and Nephrology and 2 Department of Pediatrics, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kyoto, 3 Department of Pediatrics, Matsushita Memorial Hospital, Osaka and 4 Kyoto City Institute of Health and Environmental Sciences, Kyoto, Japan

Correspondence and offprint requests to: Masashi Nishida, MD, PhD, Department of Pediatric Cardiology and Nephrology, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan. Email: mnishida@koto.kpu-m.ac.jp

Keywords: focal segmental glomerulosclerosis; monosomy 7; myelodysplastic syndromes; oligodendroglioma

The first 10% of the full text of this article appears below.



   Introduction
 
Myelodysplastic syndromes (MDS) are a group of heterogeneous clonal stem cell disorders characterized by abnormal differentiation and maturation of bone marrow haematopoietic cells. These disorders show a wide range of clinical and haematological features, and are sometimes accompanied by immunological and paraneoplastic disorders including vasculitis, autoimmune phenomena and classic connective tissue disorders [1]. Although MDS have been described mainly in adults, it has now been increasingly recognized in children [2]. However, various forms of glomerular disease associated with MDS that have been reported in adults remain rare in children [3–7]. We report here a girl with MDS accompanied by focal segmental glomerulosclerosis (FSGS). This is the first case of FSGS associated with MDS.



   Case
 
A 15-year-old girl was referred to hospital because of generalized seizure, . . . [Full Text of this Article]



   Discussion
 

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