Nephrol Dial Transplant (2003) 18: 1217-1219
© 2003 European Renal Association-European Dialysis and Transplant Association
Teaching Point(Section Editor: K. Kühn)
Solving electrolyte disturbances with the Ehrlich reagent
HELIOS Klinikum Berlin, Franz Volhard Clinic and First Department of Internal Medicine, Medical Faculty of the Charité, Humboldt University of Berlin, Berlin, Germany
Keywords: hyponatraemia; porphyria; urine
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Case
A 57-year-old female was admitted because of poorly controlled hypertension and dyspnoea when climbing stairs. She had been given a thiazide diuretic, a calcium antagonist and an angiotensin converting enzyme inhibitor. On further questioning she indicated that she had a life-long history of intermittent abdominal discomfort. She had moderate hypertensive eyeground changes. Her electrocardiogram was non-specific; however, an echocardiogram was consistent with moderate cardiac hypertrophy and diastolic dysfunction. Her serum sodium was 127 mmol/l. Her urine appeared normal and her urinalysis was normal with the exception of a highly positive urobilinogen determination on the test-strip [1]. The life-long history of intermittent abdominal pain together with the appearance of high amounts of urobilinogen raised our suspicion for porphyrins. Therefore, we performed a simple test using Ehrlich's reagent. The appearance of her urine,
Discussion
Teaching point