Nephrol Dial Transplant (2003) 18: 378-383
© 2003 European Renal Association-European Dialysis and Transplant Association
Prospective evaluation of failure modes in autogenous radiocephalic wrist access for haemodialysis
1 Department of Surgery, 2 Department of Nephrology, 3 Department of Radiology, University Hospital Maastricht, The Netherlands and 4 Department of Surgery, Medical Center Zuid Rotterdam, The Netherlands
Introduction. Radiocephalic wrist arteriovenous fistulae (RCAVF) are the primary and best option for vascular access for haemodialysis treatment. However, 1024% of these AVFs fail due directly to thrombosis and non-maturation. In a prospective study, the failure modes of radiocephalic AVFs and the impact of surgical and interventional treatment on fistula outcome were investigated.
Methods. The rate of thrombosis and non-maturation was evaluated in 43 RCAVFs. The selection of RCAVF creation was made on preoperatively determined duplex parameters. Fistula function was evaluated post-operatively by clinical examination and non-invasively measured AVF blood flow. A policy of a liberal use of radiological and/or surgical revision of non-functioning RCAVFs was made on the basis of duplex measured blood flow and angiographically detected vessel stenosis.
Results. Primary fistula function was achieved in 26 of 43 patients (60%). Non-maturation and thrombosis occurred in 14 (33%) and three (7%) patients, respectively. A total of 12 interventions (PTA 6; surgery 6) were needed, resulting in salvage of eight RCAVFs (47%). The blood flow in functioning AVFs was significantly higher compared to non-functioning AVFs at 1 (754 vs 440 cc/min), 7 (799 vs 524 cc/min) and 42 days (946 vs 532 cc/min) post-operatively. At the end, 34 RCAVFs (79%) became functional as vascular access for haemodialysis treatment.
Conclusion. Primary RCAVFs have a high rate of failure. An aggressive approach towards early interventional treatment of these non-functional AVFs is worthwhile and leads to a considerable salvage rate. Early post-operative AVF flow measurement indicates the chance of successful maturation of RCAVF.
Keywords: fistulae; haemodialysis; intervention; non-maturation; radiocephalic vascular access
Correspondence and offprint requests to: Dr J. H. M. Tordoir, P. Debyelaan 25, 6202 AZ Maastricht, The Netherlands. Email: j.tordoir{at}surgery.azm.nl
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