Nephrol Dial Transplant (2003) 18: 2688-2690
© 2003 European Renal Association-European Dialysis and Transplant Association
Letter
Risks related to catheter locking solutions containing concentrated citrate
1Oberdorf-Malerweg 12 Köstenberg Austria 2Dialysis Centre Lahr Ettenheim Germany Email: pg@compuserve.com
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Sir,
We are concerned that risks of using concentrated sodium citrate for a catheter lock solution (CIT) are not well understood. Routine haemodialysis is safe, partly as a result of European Standards requiring medical devices to be safe even under fault conditions [1]. Risk analysis taking foreseeable user errors (FUE) into account is part of the process of obtaining approval to market a new medical product. Medical practitioners are not bound to this process and may neglect the effects of user errors.
During development of a low concentration citrate-containing lock solution we carried out
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