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Nephrol Dial Transplant (2003) 18: 2684-2685
© 2003 European Renal Association-European Dialysis and Transplant Association

Letter

Proximal tubular cells: potential role in macrophage migration and crescent formation

Ladislava Grcevska1, Gordana Petrusevska2, Momir Polenakovic1 and Sonja Dzikova1

1Department of Nephrology Clinical Center 2Institute of Pathology Faculty of Medicine Skopje Republic of Macedonia Email: maknefpo@nic.mpt.com.mk

The first 10% of the full text of this article appears below.

Sir,

Tubulointerstitial disease is a consistent feature of progressive glomerular injury. However, the mechanism by which inflammatory events in the glomerulus involve the tubulointerstitium remain poorly understood. Recent data suggest that proximal tubular epithelial cells are important in the mediation of this process [1–3]. Proximal tubular cells play an important role in local macrophage proliferation; they are a major site of macrophage colony-stimulating factor (M-CSF) . . . [Full Text of this Article]


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