Nephrol Dial Transplant (2003) 18: 187-189
© 2003 European Renal Association-European Dialysis and Transplant Association
Case Reports
Acute cytomegalovirus infection complicated by collapsing glomerulopathy
1 Department of Renal Medicine, 2 Department of Medical Microbiology and 3 Department of Histopathology, St George's Hospital Medical School, London, UK
Keywords: collapsing glomerulopathy; end-stage renal disease; focal segmental glomerulosclerosis; primary cytomegalovirus infection; renal injury
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| Introduction |
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Collapsing glomerulopathy (CG) is a renal injury described initially in association with HIV-induced nephropathy but also seen increasingly in non-HIV-infected individuals. Some authors recognise it as a separate clinicopathological variant of focal segmental glomerulosclerosis (FSGS) associated with nephritic syndrome, rapidly progressive chronic renal failure and the histopathologic features of glomerular capillary collapse [1,2]. It has also been linked with other viral infections including hepatitis C, but to date not with cytomegalovirus (CMV). There may be an association with lymphoproliferative disorders and autoimmune disease, but this is less certain [3]. We report the first case
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