Nephrol Dial Transplant (2002) 17: 1166-1169
© 2002 European Renal Association-European Dialysis and Transplant Association
Editorial Comments
Hypertension after kidney transplantation: are treatment guidelines emerging?
Medical Department, Nephrology Section, Rikshospitalet University Hospital, Oslo, Norway
Keywords: hypertension; renal transplantation; treatment guidelines
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Introduction
Hypertension after renal transplantation is a strong predictor of patient and graft survival, but European guidelines for treatment of post-transplant hypertension have not yet been put forward. However, with the present knowledge, including data from recent intervention studies, there is a basis for future therapy guidelines. Here we address some important aspects of hypertension and its treatment after kidney transplantation.
Definition of post-transplant hypertension
In transplant recipients, hypertension is usually defined as blood pressure >140/90 mmHg or likewise if a patient is treated with antihypertensive drugs [1,2]. A cut-off at 150/90 mmHg has also been proposed [3]. We prefer the first definition, which is probably the most widely accepted cut-off value for primary hypertension in the general population [4]. Some centres use the blood pressure criteria of the World Health Organization/International Society of Hypertension (>130/85 mmHg) [5].
Incidence and pathophysiology of post-transplant hypertension
Prior to the introduction of cyclosporine as
Impact of post-transplant hypertension
Drug treatment of hypertension after transplantation
Left ventricular hypertrophy and combination therapy
Treatment goals
Summary
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