Nephrol Dial Transplant (2002) 17: 1025-1031
© 2002 European Renal Association-European Dialysis and Transplant Association
The Marmara earthquake: admission laboratory features of patients with nephrological problems
ükrü Sever1,
ol Canbakan9
1 Department of Nephrology, 
stanbul School of Medicine, stanbul, Turkey,
2 Department of Nephrology, Cerrahpasa School of Medicine, stanbul, Turkey,
3 Renal Disaster Relief Task Force, Renal Division, University Hospital, Ghent, Belgium,
4 Department of Nephrology, Marmara School of Medicine, stanbul, Turkey,
5 Department of Nephrology, Uluda
School of Medicine, Bursa, Turkey,
6 Department of Nephrology, Göztepe Social Security Hospital, stanbul, Turkey,
7 Department of Surgery, Osman Gazi School of Medicine, Eskiehir, Turkey,
8 Department of Nephrology, stanbul School of Medicine, stanbul, Turkey,
9 Department of Nephrology, Ankara Numune Hospital, Ankara, Turkey,
10 Department of Nephrology, Gazi School of Medicine, Ankara, Turkey and
11 Renal Disaster Relief Task Force European Branch, University Hospital, Ghent, Belgium
Background. Earthquakes are major causes of morbidity and mortality. North-western Turkey was struck by a devastating earthquake in August 1999, which caused several thousand deaths. Among the most important morbid events in survivors were acute nephrological problems.
Methods. Within the first week of the disaster, specific questionnaires asking about 63 clinical and laboratory parameters were sent to 35 reference hospitals that were treating the victims. Of the registered 639 victims, 423 were admitted within the first 3 days of the disaster; the admission laboratory data of these 423 patients are the subject of this analysis.
Results. In the 423 patients (233 males, mean age 31.3±14.4 years), time under the rubble was 10.7±10.4 h. Mean values at admission were as follows: serum potassium 5.4±1.3 mEq/l, creatine phosphokinase 58205±77889 IU/l, albumin 2.6±0.7 g/dl, phosphorus 5.2±1.8 mg/dl, haematocrit 35.0±9.3%, leukocyte count 14945±6614/mm3, platelet count 183975±134012/mm3, blood urea nitrogen 55.1±28.9 mg/dl, and creatinine 3.9±2.3 mg/dl. Serum potassium above 6.5 mEq/l was noted in 91 patients (22.7%), an alarming finding for risk of fatal arrhythmias. Non-survivors were characterized by higher figures of serum potassium (P=0.001), as well as lower haematocrit (P=0.028), platelets (P<0.001), and serum albumin (P=0.003). In a multivariate analysis model of admission laboratory parameters, serum creatinine (P<0.001, o.r.=2.19), potassium (P=0.001, o.r.=3.64), and phosphorus (P=0.004, o.r.=1.78) predicted dialysis needs, whereas serum albumin (P=0.028, o.r.=0.23) and creatinine (P=0.039, o.r.=0.60) were related to mortality.
Conclusions. Admission laboratory data may be useful for predicting dialysis needs and survival chance of disaster victims. High incidences of some life-threatening abnormalities dictate the need for empirical therapy even in the field.
Keywords: acute renal failure; crush syndrome; dialysis; hyperkalaemia; laboratory findings; Marmara earthquake
Correspondence and offprint requests to: Dr Mehmet ükrü Sever, Ataköy, 4. Kisim, TO Blok, No. 216, D:15, Bakirköy, stanbul, 34750, Turkey. Email: severm{at}hotmail.com
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