Nephrol Dial Transplant (2002) 17: 703-707
© 2002 European Renal Association-European Dialysis and Transplant Association
Editorial Comments
Pregnancy after renal transplantation: points to consider
Department of Nephrology, Dialysis and Transplantation, Tehran University of Medical Science, Tehran, Iran
Keywords: pregnancy; renal transplantation
Introduction
Women with chronic renal failure suffer from loss of libido, anovulatory vaginal bleeding or amenorrhea and high prolactin levels [1]. On dialysis most experience decreased libido and reduced ability to reach orgasm [2–4]. Conception is rare for women on dialysis. It occurs at a rate of no more than one in every 200 patients [5].
Fertility is usually restored in women with renal transplants. Pregnancy is then common, occurring in 12% of women at childbearing age in one series [6]. Pregnancy success rate exceeds 90% after the first trimester. The recovery of fertility is less common in women who undergo transplantation close to the end of their childbearing years [3]. The first reported successful pregnancy occurred in a recipient of a kidney transplant from an identical twin sister performed in 1958 [7]. Since then, there have
Effect of pregnancy on graft function
Immunosuppressive drugs in pregnancy
Glucocorticoids
Azathioprine
Cyclosporin
Tacrolimus
Mycophenolate mofetil
OKT3 and polyclonal antibodies
Management guidelines
Management of hypertension
Antihypertensive drugs used in pregnancy
-Methyldopa
Beta Blockers
Hydralazine
Calcium channel blockers
Labetalol
ACE inhibitors
Diuretics
Management of infection
Bacterial
Viral
Labour and delivery
Conclusion
Notes
References
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