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Nephrol Dial Transplant (2002) 17: 528-529
© 2002 European Renal Association-European Dialysis and Transplant Association

Letters

Accumulation of taurine in patients with renal failure

Mohamed E. Suliman, Peter Bárány, José C. Divino Filho, Bengt Lindholm and Jonas Bergström

Divisions of Baxter Novum and Renal Medicine Department of Clinical Science Karolinska Institutet Huddinge University Hospital Stockholm, Sweden

Sir,

The amino acid taurine (2-aminoethanesulphonic acid) is present in high concentrations in mammalian tissues, especially skeletal muscle, heart and the central nervous system. Taurine has several beneficial physiological and biochemical effects in vitro and in vivo in experimental animals. It has cardiotonic actions, participates in osmoregulation, stabilizes the membrane potential in skeletal muscle, affects calcium ion kinetics, has antioxidant and anti-inflammatory properties and acts as a neurotransmitter [1]. Clinical studies suggest . . . [Full Text of this Article]

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