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Nephrol Dial Transplant (2002) 17: 321-322
© 2002 European Renal Association-European Dialysis and Transplant Association

Letters

Isolated pleural involvement by Cryptococcus in a kidney–pancreas transplant recipient

Venkataraman Ramanathan1, Rumeyza Kazancioglu1, Simin Goral1, Stephen Dummer2 and J. Harold Helderman1

Department of Medicine, Divisions of 1 Nephrology and 2 Infectious Diseases, Vanderbilt Transplant Center, Vanderbilt University, Medical Center, Nashville, TN, USA

Sir,

In the modern era of solid organ transplantation, vigorous efforts are aimed at reducing acute rejection rates with ever more potent immunosuppressive drugs. As a consequence, the physician often must deal with the adverse effects of excessive immunosuppression including opportunistic infections. Infections in the peri-engraftment period are commonly bacterial in origin, while, a few months later, the incidence of opportunistic fungal infections increases due to the defects in cell-mediated immunity [1]. We present a case of a kidney–pancreas transplant recipient with an asymptomatic pleural effusion, which was caused by Cryptococcus neoformans. Isolated pleural involvement with Cryptococcus has not been reported previously in kidney–pancreas or kidney transplant . . . [Full Text of this Article]

Case.

Comment.

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