Nephrol Dial Transplant (2002) 17: 319-321
© 2002 European Renal Association-European Dialysis and Transplant Association
Letters
Parkinsonism during cyclosporine treatment in renal transplantation
1 Department of Internal Medicine, Dongsan Kidney Institute, 2 Department of Radiology, Keimyung University, Dongsan Medical Center, Taegu, Korea
Sir,
Cyclosporin (CyA), a lipophilic, cyclic oligopeptide that modulates T-cell function, is a potent immunosuppressive agent [12]. A variety of neurological complications have been associated with CyA, including seizures, headaches, encephalopathy, cortical blindness, visual hallucinations, and tremor [14]. Parkinsonism is not generally recognized as a nervous system complication of CyA. Recently Wasserstein and Honig [5] first reported two cases of parkinsonism during CyA treatment following allogenic bone marrow transplantation. To the best of our knowledge, there has been no reported case in the literature documenting the
Case.
Comment.
References