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Nephrol Dial Transplant (2001) 16: 1719-1720
© 2001 European Renal Association-European Dialysis and Transplant Association

Letters and Replies

Timing of sildenafil therapy in dialysis patients

Richard Siegel and Eric Grossman

Pfizer Inc., New York, USA

Sir,

Dr Mohamed has described a case of hypotension in a 49-year-old haemodialysis (HD) patient during an inter-dialysis day on which he took a 50 mg dose of sildenafil citrate (Viagra®) and concludes that sildenafil was the most likely cause of this event [1]. As with many spontaneously reported adverse events, it is difficult to determine causality from the description given. In this case, the patient began to ‘feel unwell, with headache, nausea, epigastric pain and flushing’ 1 h after ingestion of sildenafil. When his blood pressure was measured the next day (12 h later), it was found to be 80/50. There . . . [Full Text of this Article]

References

R. A. Coward and E. A. Mohammed

Department of Renal Medicine, Royal Preston Hospital, Preston, UK


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