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Nephrol Dial Transplant (2001) 16: 1675-1680
© 2001 European Renal Association-European Dialysis and Transplant Association

Is the loss of health-related quality of life during renal replacement therapy lower in elderly patients than in younger patients?

Pablo Rebollo1,, Francisco Ortega1, José María Baltar1, Fernando Álvarez-Ude2, Rafael Alvarez Navascués1 and Jaime Álvarez-Grande1

1 Nephrology Unit of the ‘Hospital Central de Asturias’ and Institute ‘Reina Sofía’ for Nephrological Research, 2 Nephrology Unit of the ‘Hospital General de Segovia’, Oviedo, Spain

Background. Previous studies have reported that elderly (aged 65 years or over) end-stage renal disease (ESRD) patients have poorer health-related quality of life (HRQOL) than both younger patients and healthy subjects of the same age. The aim of present study was to evaluate the effect of ESRD and its treatment on the HRQOL, and to determine the effects of age and gender.

Methods. A cross-sectional multicentric study was carried out with 485 haemodialysis and renal-transplant patients, using the SF-36 Health Survey to evaluate their HRQOL. SF-36 scores were standardized by age and gender using Spanish normative data. Karnofsky scale score (KS), socio-demographic, and clinical data were also collected.

Results. In renal-replacement therapy (RRT), chronic haemodialysis, and renal-transplant patients, SF-36 standardized scores of elderly patients were higher than in younger patients. Therefore the reduction in HRQOL of elderly patients, in relationship with that of the general population of the same age and gender, was lower than in younger patients. In the case of renal-transplant patients, standardized scores in elderly patients were higher than in the general population for all parameters.

Conclusions. Using standardized scores, elderly patients on renal replacement therapy (haemodialysis and kidney transplant) had relatively better HRQOL than younger patients, and in the case of transplant patients, they had even better HRQOL than in the general population of the same age and gender.

Keywords: elderly; health related quality of life; haemodialysis; kidney transplant; renal replacement therapy

Correspondence and offprint requests to: Dr Pablo Rebollo, Servicio de Nefrología I, Hospital Central de Asturias, C/Celestino Villamil S/N, 33006 Oviedo, Spain.


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