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Nephrol Dial Transplant (2001) 16: 1087
© 2001 European Renal Association-European Dialysis and Transplant Association

Letters

Severe methotrexate intoxication in a haemodialysis patient treated for rheumatoid arthritis

Henri Boulanger1, Vincent Launay-Vacher1, Philippe Hierniaux2, Jean-Baptiste Fau1 and Gilbert Deray1

1 Department of Nephrology, Pitie-Salpetriere Hospital, Paris, France 2 Clinique du Plateau, Bezons, France

Sir,

Methotrexate is extensively used in the treatment of neoplastic diseases. It is a folic acid antagonist that inhibits the dihydrofolate reductase involved in the synthesis of puric and pyrimidic bases [1]. Methotrexate is also used at low doses in the treatment of severe rheumatoid . . . [Full Text of this Article]

Case.

Comment.

References


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