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Nephrol Dial Transplant (2001) 16: 1059-1061
© 2001 European Renal Association-European Dialysis and Transplant Association

Case Report

Renal failure in a patient with leukaemic infiltration of the kidney and polyomavirus infection

Neil Boudville, Bruce Latham, Frank Cordingly and Kevin Warr

Royal Perth Hospital, Wellington Street, Perth WA, Australia

Keywords: chronic lymphocytic leukaemia; epithelial intracytoplasmic inclusions; epithelial intranuclear inclusions; leukaemic infiltration of kidney; polyomavirus; renal dysfunction



   Introduction
 
Leukaemic infiltration of the kidney has been demonstrated on autopsy in 60–90% of patients with chronic lymphocytic leukaemia (CLL) [1,2]. This is rarely associated with renal dysfunction, with only a few case reports in the literature documenting renal failure secondary to leukaemic infiltration in CLL [3–6].

The polyomaviruses BK and JC are found ubiquitously, with most individuals acquiring the infection in childhood [7]. The disease at this stage is usually subclinical. Polyomavirus infections, thought to be primarily reactivation, have been shown to cause renal dysfunction [8–11]. This has mostly been in the context of immunosuppression, especially with renal and bone-marrow transplantation [8–11].

In this paper we describe . . . [Full Text of this Article]



   Case
 


   Discussion
 


   Notes
 


   References
 

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