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Nephrol Dial Transplant (2001) 16: 156-159
© 2001 European Renal Association-European Dialysis and Transplant Association

Case Reports

Spontaneous remission of HCV-induced cryoglobulinaemic glomerulonephritis

Bertrand Dussol,1, Valérie Moal1, Laurent Daniel2, Christian Pain3 and Yvon Berland1

1 Service de Néphrologie et Hémodialyse, Hôpital Sainte Marguerite, Marseille, 2 Service d'Anatomie Pathologique, Hôpital Timone, Marseille, and 3 Centre d'Hémodialyse Sainte Marguerite, La Garde, France

Keywords: glomerulonephritis; hepatitis C virus infection; type II mixed cryoglobulinaemia



   Introduction
 
The association between hepatitis C virus (HCV) infection and cryoglobulinaemic membranoproliferative glomerulonephritis (cryo-MPGN) has been described in many reports [1–3]. The clinical presentation and evolution of the renal disease may be variable [1].

This report describes the unusual course of cryo-MPGN in a patient suffering from chronic HCV infection. Since our patient spontaneously recovered his renal function after 6 months of dialysis, treatments of cryo-MPGN should take into account the highly unpredictable evolution of the glomerulonephritis.



   Case
 
A 53-year-old man underwent renal evaluation in October 1996 for nephrotic syndrome and progressive renal failure.

His medical history was remarkable since chronic viral C hepatitis was diagnosed in 1991 and uncomplicated non-insulin-dependent diabetes mellitus (NIDDM) in 1993. Liver biopsy in 1991 revealed severe chronic hepatitis (Knodell score 13) and interferon-{alpha} (3 million units s.c. three times weekly) was prescribed. After 6 months, interferon-{alpha} was stopped because of . . . [Full Text of this Article]



   Discussion
 


   Notes
 


   References
 

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