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Nephrol Dial Transplant (2000) 15: 1056-1059
© 2000 European Renal Association-European Dialysis and Transplant Association

Case Reports

Minimal change nephrotic syndrome associated with rifampicin treatment

Keisuke Kohno, Yoshihiko Mizuta, Tomoyo Yoshida, Hisashi Watanabe, Hidemi Nishida, Kei Fukami, Syuuji Iida, Reiko Haramaki, Yoshifumi Wada, Osamu Tamai, Kiyoshi Tamaki, Seiya Kato1, Minoru Morimatsu1 and Seiya Okuda

Department of Internal Medicine III and 1 Department of Pathology, Kurume University School of Medicine, Fukuoka, Japan

Keywords: minimal change nephrotic syndrome; rifampicin



   Introduction
 
Rifampicin is a commonly used anti-tuberculosis agent which has been reported to have some adverse effects, including nephrotoxicity [1–9]. The most frequent form of nephrotoxicity is a syndrome consisting of acute renal failure, with tubular necrosis as pathological finding, with or without haemolysis and thrombocytopenia, generally occurring during intermittent or interrupted treatment. Other forms of nephrotoxicity are interstitial nephritis with or without mild glomerular lesions, rapidly progressive glomerulonephritis and light chain proteinuria [3]. We herein report a case of minimal change nephrotic syndrome (MCNS) after rifampicin treatment which was not associated with acute interstitial nephritis or any other glomerular lesion, followed by . . . [Full Text of this Article]



   Case
 


   Discussion
 


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   References
 

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