Nephrol Dial Transplant (2000) 15: 923-924
© 2000 European Renal Association-European Dialysis and Transplant Association
Letters
Nephrotic syndrome associated with isotretinoin
1 Department of Medicine 2 Department of Dermatology, Albert Schweitzer Hospital, Location Amstelwijck Dordrecht, The Netherlands
Sir,
Isotretinoin, a synthetic retinoid, is now used commonly in the treatment of moderate to severe acne, poorly responsive to antibiotics and local therapy [1]. Known adverse effects are: cheilitis, dry lips, dry mouth, conjunctivitis, xerosis, pruritis, hair thinning, nausea and vomiting, pain and tenderness of the bones, and headache [2]. Changes in liver function tests and lipid profile are also noted [2].
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